I use PCLinuxOS and the only thing available in the repositories is F-Prot & Kclamav. I use F-Prot.

F-Prot now has what many consider the #1 AV expert (ex NOD32 guru-AV God) so its on its way to the top. He's known as Inspector Clouseau http://www.av-experts.org/weblog/

Any of the other AV's I mentioned are very good