**this is important**
DISCONNECT THE PC FROM THE INTERNET

The malwares in question usually re-download themselves from the interweb if any part of them successfully start - so it looks fine one minute then all of a sudden it is re-infected. As they also install layers of startups you need to run several tools to be happy before you reconnect.

The roguefix script is a very good starting place as it is comparatively quick to run and will drastically cut down the poot from your PC enabling the other tools to run faster so we get to the end result (cleaned PC) faster.